Yes. Windows 10 is certified with all current EBS releases, including EBS 12.1 and 12.2. This new delivery method is not expected to change that.
Microsoft emphasizes that nothing changes with Windows 10 itself -- this only modifies the way that Win10 patches are delivered:
It’s important to note that with UUP, nothing will look or behave differently on the surface, UUP is all underlying platform and service optimization that happens behind the scenes.
The preceding is intended to outline our general product direction. It is intended for information purposes only, and may not be incorporated into any contract. It is not a commitment to deliver any material, code, or functionality, and should not be relied upon in making purchasing decision. The development, release, and timing of any features or functionality described for Oracle’s products remains at the sole discretion of Oracle.